Since December of 2014, state and federal regulatory officials have been dealing with the incursion of Highly Pathogenic Avian Influenza virus (HPAI) in both wild and domestic birds in the US. The earliest reports concerned a small number of ill captive falcons in Washington State and appeared to be limited to the Pacific Flyway. A short time later disease appeared in both the Mississippi and Central Flyways. We are currently dealing with a catastrophic outbreak affecting millions of birds and the US economy as well. Fortunately, the current risk of spread of Avian Influenza to people is considered to be low and no people have become ill at this time.